In a clinical trial of Nasonex, 300 allergy patients were randomized into two groups, with Group 1 receiving the Nasonex drug (200 mg) and Group 2 receiving a placebo. The experimenter used a 2:1 randomization plan so that more subjects would be assigned to the Nasonex group. One outcome of interest is the incidence rate of headache as a side-effect. Of the 200 patients randomized to the Nasonex group, 52 (or 26%) reported experiencing a headache; and of the 100 patients randomized to the placebo group, only 22 (22%) reported a headache.
a. A researcher plans to make a 95% confidence interval to estimate the difference in the headache rates for the population of all Nasonex patients versus population of all placebo patients. To use the multiplier of z* = 1.96, it must be determined if the sample sizes are large enough. This verification is slightly different than that for conducting a test of hypotheses. Provide sufficient verification for the use normality to construct the confidence interval.
In the calculation of the confidence interval, we need to obtain the standard error of 1 – 2. Provide that standard error.
C. Provide the 95% confidence interval to estimate p1 – p2, the difference in the headache rates for the population of all Nasonex patients versus the population of all placebo patients. (1.5 pts)
D. Based on the interval, at a 5% significance level, does there appear to be a significant difference in the headache rates for the two populations of all Nasonex patients versus the population of all placebo patients? State your answer as yes or no and then provide a brief rationale for your answer.
Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.
You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.Read more
Each paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.Read more
Thanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.Read more
Your email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.Read more
By sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.Read more